It is now generally accepted that burn blisters should not be left because the blister fluid exerts pressure on the burn, which then affects the microcirculation and impedes healing. The London and South East England Burn Network recommends deroofing all large and thin-walled blisters, but apparently “the benefits of aspiration vs deroofing have been discussed for many years by medical experts“ (according to this paper). Might this be a possible alternative?
Medicine, April 2018