A high-quality systematic review is the most reliable source of evidence to help clinical decision making. This presentation will briefly discuss the steps, best practices, and strategies for conducting a systematic review in a smaller library setting or for a solo librarian with multiple job roles in an academic medical center. The most important elements such as librarian’s role and collaboration strategies, research question development, searching and data management, helpful standards and tools, and getting the work published etc. will be discussed.

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