Welcome to Guts and Glory, the surgical podcast hosted by Dr. Sadiq Sikora. In this episode, titled “Confusion at the Junction – GE Junction Conundrum”, Dr. Sikora is joined by Prof. Inian Samarasam, Professor of Surgery and Chief of Upper GI Surgery at the prestigious CMC Vellore. Together, they engage in a comprehensive discussion on the nuanced challenges of tumors at the gastroesophageal junction. The conversation delves into the latest strategies for diagnosis, classification, and operative management, emphasizing how the precise location of the tumor influences surgical approach, resection margins, and reconstruction techniques. This episode brings expert insights and evidence-based analysis for surgeons navigating the evolving landscape of GE junction tumors.