In the inaugural episode of MMI Monthly: From Bench to Breakthrough, guest host Thomas Locke explores the evolution of COVID-19 convalescent plasma (CCP) therapy, from starting as an idea at the School of Public Health, to its emergency use during the COVID-19 pandemic to now, four years later, crossing the finish line with its recent FDA approval as a potent treatment for immunocompromised patients. Featuring Professor David Sullivan, the podcast delves into the science behind convalescent plasma, its life-saving potential, and its role in protecting those most vulnerable. Could this breakthrough offer a blueprint for future pandemics?