Vidcast:  https://youtu.be/oTO39cwGbqQ

 

Vaccination with either the Moderna or the Pfizer mRNA vaccines triggers strong but gradually declining CoVid antibody and cell-mediated responses.  University of  Pennsylvania researchers studied the immune responses of 61 vaccinated individuals at 6 time-points: pre-vaccine to 6 months after the jab.  Sixteen of the 61 vaccine recipients were vaccinated after surviving CoVid.

 

The peak antibody levels were measured 1 week after the second dose.  Then, over the first 3 months following vaccination, the antibody levels dropped by one-half every 35 days.  Over the second 3 months, the antibody levels dropped by one-half every 60 days.  All those vaccinated did have detectable antibody by 6 months.  A gratifying finding is that populations of B cells that manufacture protective anti-Covid antibodies to CoVid variants actually increased over 3-6 months post-vaccination.  This indicates that the vaccine, made against so-called wild-type CoVid, triggers a response capable of responding to changing virus and more dangerous variants.

 

Cell-mediated anti-CoVid activity peaked one week after vaccination completion and then dropped from then until 3 months but was still present at 6 months.  Despite a decrease in virus killer cell numbers, there is evidence that these cells remain ready to rise to the occasion and kill on demand.

 

https://www.biorxiv.org/content/10.1101/2021.08.23.457229v1.full.pdf

 

 

#CoVid #vaccine #antibodies #cellmediatedimmunity #variants