Our hosts investigate the relationship between micro-dosing and creativity through the lens of professional artists, musicians, and writers. Host A presents a series of creative output analyses from before and during artists' micro-dosing experiments, while Host B examines neuroscience research on psychedelics and creative cognition. The discussion covers specific dosing protocols used by different creative professionals, measures of creative output quality versus quantity, and the challenge of objectively assessing artistic enhancement. The episode concludes with an examination of historical examples of psychedelic use in art and their modern parallels.