AUTM on the Air

CRISPR Breakthroughs in Tuberculosis and Tech Transfer with Dr. Valwynne Faulkner


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This episode will illustrate how scientific research and tech commercialization can create a powerful impact. I'm excited to have Dr. Valwynne Faulkner on the show today. She is a postdoctoral researcher at the Francis Crick Institute and a LifeArc Knowledge Transfer Innovations Fellow. Her fascinating work spans cutting-edge molecular biology research and technology transfer.

Val walked me through the work her team is doing with CRISPR to expose new ways of tackling tuberculosis, even the stubborn drug‑resistant strains. She also opened up about how the LifeArc fellowship is pulling her deeper into tech transfer, what she is learning about patents and partnerships, and why she thinks regulators need a seat at the table from day one.

Whether you spend your days at the bench or in an office turning ideas into products, Val’s story shows how a curious mind and a collaborative spirit can move discoveries out of the lab and into the world.


In This Episode:

[01:12] We learn about Dr. Faulkner's current research at the Francis Crick Institute studying mycobacterium tuberculosis. 

[01:50] At the systems chemical biology lab they are developing CRISPR-based molecular tools that we can use to precisely control and silence genes.

[02:13] This helps them understand the functional roles of genes in TB and response to antimicrobial drugs.

[03:05] The hope is that the research will uncover new drug targets and help combat antimicrobial drug resistance.

[03:46] Dr. Faulkner talks about the LifeArc Knowledge Transfer Innovations Fellowship. It helps teach scientists how to transition into careers within tech transfer. They get formal training and all aspects.

[05:14] She learned about the program by chance. LifeArc was at the Francis Crick for a career event. 

[06:15] Her diverse experience across academia, industry and regulatory labs has given her a holistic perspective on research translation.

[07:38] AUTM is a partner with the fellowship and gives them access to all of the online tools and learning centers. Along with excellent mentors and experienced professionals.

[08:40] Insights gained from the AUTM 50th event. It's amazing how many stakeholders are involved.

[09:37] Bridging the gap between scientific research and commercialization. The AUTM  Annual meeting has been crucial in facilitating knowledge exchange and networking.

[10:49] A key challenge is navigating the complicated IP landscape. 

[11:57] Dr. Faulkner is excited about advancements in antimicrobial drug discovery.

[13:04] Advice includes reaching out and asking questions and seeking things like fellowships. Be open to interdisciplinary collaborations.

[13:53] The future of research innovation will be shaped by strong academic and commercial partnerships.


Resources: 

Dr. Valwynne Faulkner - Francis Crick Institute

LifeArc


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