(AI Generated Summary) The sermon explores the biblical concept of the new birth and the necessity of a transformed heart for salvation. It defines the heart as the center of intellect, desire, and will, illustrating how humanity's innate pursuit of happiness is misdirected toward self rather than God. By examining examples like Eve and the crucifixion, the message demonstrates that sin stems from wrong thinking about what brings true good. The preacher argues that genuine joy is found only in obeying God and seeking His steadfast love. Ultimately, regeneration is presented as the divine solution to replace the deceitful heart of stone with a responsive heart of flesh.