In this episode of Curing with Sound, we explore a groundbreaking approach to one of medicine’s toughest cancers, glioblastoma (GBM), with Michael Canney, PhD, Chief Scientific Officer at Carthera. GBM is the most aggressive form of brain cancer, notoriously hard to treat because the blood-brain barrier (BBB) blocks many life-saving drugs from reaching tumor cells. With survival rates of just one to two years, new approaches are urgently needed.

Dr. Canney shares how Carthera’s SonoCloud-9, an implantable, therapeutic ultrasound device, temporarily opens the BBB and enhances the delivery of circulating drugs to the brain. He also discusses the SONOBIRD clinical trial, comparing the use of Carthera’s SonoCloud-9 device combined with chemotherapy to standard-of-care therapies in patients with recurrent GBM.

EPISODE TRANSCRIPT

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Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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In this episode of Curing with Sound, we sit down with Gary Shapiro, CEO and Vice Chair of the Consumer Technology Association (CTA), and a valued member of the Focused Ultrasound Foundation Board of Directors. With decades of experience advocating for disruptive innovation, Gary offers a unique perspective on how focused ultrasound fits within the global ecosystem of transformative healthcare technologies. His perspective provides a compelling look at how focused ultrasound aligns with broader trends in global healthcare innovation.

Throughout the conversation, Gary shares his personal journey, from his work in technology policy and innovation leadership to his role on the Foundation’s board, where he continues to advocate for the rapid expansion and adoption of focused ultrasound worldwide. His insights reflect both the urgency and the opportunity of bringing transformative technologies into mainstream healthcare. 

Discussion highlights:

EPISODE TRANSCRIPT

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Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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In this episode of Curing with Sound, we meet Melissa McGinnis, an essential tremor patient whose life was transformed through focused ultrasound treatment. Melissa endured decades of progressive tremors that impacted every aspect of daily life since her diagnosis as a child–a rare occurrence for those with the condition.

After learning about focused ultrasound during its clinical trials in 2012 and waiting over a decade for the treatment to become available, Melissa finally received the treatment in January 2025. The results were immediate and dramatic, providing her with greater independence and the ability to complete everyday tasks that were once a challenge. 

Discussion highlights:

Follow Melissa's journey on her YouTube channel: @MMCshakesalot

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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FUSF WEBSITE

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

FUSF SOCIAL MEDIA

FUSF WEBSITE

Joining him is Nick Marinelli, an Iraq War veteran and Black Hawk mechanic who participated in Dr. Philip’s revolutionary clinical trial after struggling with depression and anxiety for over a decade following his deployment. Nick shares his experience receiving focused ultrasound treatments and the immediate improvements he noticed in his daily mood and his ability to be present with his family, particularly during meaningful moments like his daughter's kindergarten graduation.

Discussion highlights:

All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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In this episode of Curing with Sound, we speak with Bill Traynor, a Canadian adventurer whose life shifted dramatically when he was diagnosed with ALS (Lou Gehrig's disease), a neurodegenerative disorder with an average life expectancy of just two to five years. Once enjoying high-impact activities like skydiving, race car driving, and scuba diving, Bill's active lifestyle came to an abrupt halt. 

Determined to face the diagnosis head-on, Bill became the first person to participate in a focused ultrasound clinical trial at Sunnybrook Research Institute, where researchers used a newly developed helmet to noninvasively and temporarily open the blood-brain barrier. This breakthrough allowed direct delivery of immunotherapy to his brain to reduce ALS-related neuroinflammation. 

Discussion highlights:

All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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In this episode of Curing with Sound, we speak with Rosie Xing, PhD, Managing Director of Global Planning, International Marketing, and Business at Chongqing Haifu Medical Technology, a world leader in noninvasive focused ultrasound systems. Founded in 1999 by Professor Zhibiao Wang, Chongqing Haifu has revolutionized treatment for patients across 400 medical centers worldwide, with their technology now installed in 32 countries outside China.

Prof. Xing shares about the growth of Chongqing Haifu, starting with the first therapeutic system to treat osteosarcoma. Now, their devices can treat conditions such as uterine fibroids, adenomyosis, and cancers of the liver, breast, pancreas, kidneys, and bones, in addition to other diseases. She also discusses the company’s collaborations with professional societies, research centers, and academic institutions worldwide.   

Discussion highlights:

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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Monica shares a candid account of her struggles with debilitating OCD, including the painful compulsions and time-consuming rituals that affected her personal and professional life. Her experience offers valuable insight into the challenges of living with treatment-resistant OCD and the life-changing potential of focused ultrasound as a breakthrough therapy for psychiatric conditions. 

Discussion highlights:

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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Dr. Horisawa also details his clinical trial using focused ultrasound for cervical dystonia, a neurological disorder causing involuntary muscle contractions in the neck that can lead to abnormal head postures and significant pain. This Foundation-funded trial demonstrated an average improvement of 43% in symptoms six months after treatment, and no serious treatment-related complications. 

Discussion highlights:

EPISODE TRANSCRIPT

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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In this episode of Curing with Sound, we explore focused ultrasound for prostate cancer through the lens of a patient and a patient advocate. Bob Palmer, who underwent the TULSA-PRO procedure - a minimally invasive, incision-free treatment - discusses his decision-making process and treatment experience. He is joined by Eve Satterthwaite, a registered nurse and patient educator at Profound Medical. She provides an overview of what patients can expect from the procedure and her role in guiding them through treatment.

Bob shares how Eve helped him evaluate treatment options after his prostate cancer diagnosis and what led him to choose TULSA-PRO, particularly in light of potential side effects associated with surgery and radiation. Eve explains how she helps patients understand their options, outlines the clinical benefits of the TULSA procedure, and addresses common patient concerns.

Discussion highlights:

All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.

Visit TULSAprocedure.com for more information

Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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