Curing with Sound

By Focused Ultrasound Foundation

Imagine harnessing the power of sound waves to heal the human body–this isn’t science fiction, it’s the reality of focused ultrasound technology. Join the conversation that explores the transformative... more

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FAQs about Curing with Sound:

How many episodes does Curing with Sound have?

The podcast currently has 56 episodes available.

Curing with Sound episodes:

June 23, 2026Ep55: Movement Disorders, Epilepsy and More: The Expanding Impact of Focused Ultrasound
Focused ultrasound is rapidly expanding the boundaries of what is possible in functional neurosurgery. From movement disorders to epilepsy, researchers are exploring how this noninvasive technology can precisely target and treat an expanding range of neurological conditions.

In this episode of Curing with Sound, Vibhor Krishna, MD, Associate Professor and Vice Chair of Inpatient Operations in the Department of Neurosurgery at the University of North Carolina, discusses the latest advances in focused ultrasound for neurological disorders. Dr. Krishna shares moving patient stories, reviews newly approved bilateral treatment for Parkinson’s disease, and shares encouraging early findings from a Phase I clinical trial for treatment-resistant epilepsy.

The conversation also explores the broader therapeutic landscape for epilepsy and the opportunities ahead as focused ultrasound research continues to advance.

Discussion highlights:
Incisionless Tremor Relief: Discover how focused ultrasound offers a life-changing, noninvasive option for patients with essential tremor who wish to avoid invasive surgery and implanted hardware.

Bilateral Parkinson's Treatment: Learn about the recent FDA approval for ablating the palatothalamic tract (PTT) bilaterally, a staged approach that addresses fluctuating symptoms like stiffness and slowness while potentially reducing medication dependence.

Pioneering Epilepsy Trials: Hear promising early results of a Phase I clinical trial using focused ultrasound to reduce seizure frequency in patients with treatment-resistant epilepsy.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
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FOCUSED ULTRASOUND TREATMENT SITES
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28min
June 09, 2026Ep54: Exploring Focused Ultrasound Applications in Veterinary Medicine with Ashish Ranjan, PhD
In this episode of Curing with Sound, we speak with Ashish Ranjan, PhD, a professor of radiation oncology and director of the Veterinary Research and Oncology Clinic at the University of Texas Southwestern. Dr. Ranjan discusses how emerging focused ultrasound applications, including histotripsy and sonodynamic therapy, are being used to treat solid tumors in companion animals.
He explains how veterinary oncology research contributes to advances in human medicine, shares findings from ongoing clinical studies, and explores the potential of combining focused ultrasound with immunotherapy, radiation therapy, and other cancer treatments. Learn how comparative oncology is helping shape the future of personalized, noninvasive cancer care for both veterinary and human patients.
Discussion highlights:
The One Health Approach: Learn how studying naturally occurring diseases in companion animals can accelerate therapeutic development, providing a powerful bridge between veterinary and human medicine and helping researchers evaluate new treatments more efficiently.

Veterinary Research and Oncology Clinic (VROC): Discover how VROC combines advanced clinical care with cutting-edge research to offer dogs and cats access to innovative cancer treatments. The clinic evaluates emerging technologies, such as focused ultrasound, and other novel therapies, and maintains a strong focus on patient comfort, quality of life, and individualized care.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
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X
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YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
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DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
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...more
27min
May 19, 2026Ep53: Microbubble Technology and Focused Ultrasound: A Conversation with Sasha Klibanov, PhD
Targeted drug delivery to the brain has long been hindered by the blood-brain barrier, a protective layer that prevents many therapeutic agents from reaching their intended targets. For patients with serious neurological disorders, this challenge can significantly reduce access to potentially effective treatments and limit therapeutic outcomes.
In this episode of Curing with Sound, we speak with Sasha Klibanov, PhD, Associate Professor in the Division of Cardiovascular Medicine at the University of Virginia and a pioneering researcher in microbubble technology. Dr. Klibanov discusses the evolution of microbubbles from imaging contrast agents to sophisticated tools for drug delivery. He also explains how focused ultrasound, combined with microbubbles, can safely and temporarily open the blood-brain barrier, creating new opportunities for precision therapies and advancing the potential of immunotherapy.
Discussion highlights:
Microbubble Technology Explained: Explore how microbubbles evolved from diagnostic imaging tools into powerful agents for precise drug delivery when combined with focused ultrasound.

Advancing Immunotherapy: Learn about Dr. Klibanov's collaborative research on using size-sorted microbubbles to optimize the opening of the blood-brain barrier, potentially revolutionizing how we treat complex diseases by enabling targeted immune responses.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
19min
May 05, 2026Ep52: Now You See It, Now You Don't: A Magician's Tremor Disappears with Focused Ultrasound
Essential tremor is a progressive neurological condition that causes involuntary shaking, often significantly impairing everyday tasks. For many, the loss of fine motor control means giving up lifelong passions and careers. Even simple actions, like buttoning a shirt, eating, or writing, can become overwhelming, leading to frustration, embarrassment, and a diminished quality of life.
In this episode of Curing with Sound, we speak with Howard Faber, a Michigan-based magician who spent decades entertaining audiences before essential tremor forced him to step away from the stage. Howard discusses his experience with focused ultrasound, a noninvasive treatment that ultimately transformed his condition.
He reflects on his journey with progressively worsening tremors, the turning point when Medicare approved focused ultrasound treatment, and his life-changing experience undergoing the procedure. Today, Howard has returned to performing, having regained complete control of his hands and his life.
Discussion highlights:
The Impact of Essential Tremor: Discover how Howard's progressive tremors interfered with his daily life and his beloved magic career, leading to moments of embarrassment and the difficult decision to stop performing.

A Life-Changing Procedure: Follow Howard's experience undergoing focused ultrasound treatment at the Cleveland Clinic, from the preparation process to the emotional moment he realized his tremor was completely gone.
All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.

EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
16min
April 21, 2026Ep51: From Research to Reality: Focused Ultrasound for Brain Tumors and Neurodegenerative Diseases
The blood-brain barrier (BBB) is a vital protective mechanism that shields the brain from harmful substances, but it also poses a significant challenge in treating neurological diseases. For patients with aggressive brain tumors or neurodegenerative conditions, the BBB can prevent life-saving therapies and chemotherapeutic agents from reaching their targets, leaving limited treatment options.
In this episode of Curing with Sound, we speak with Ying Meng, MD, PhD, a neurosurgeon and scientist at Sunnybrook Health Sciences Centre and the University of Toronto. Dr. Meng is at the forefront of advancing noninvasive brain therapies, leading efforts to translate preclinical focused ultrasound research into clinical application. She shares insights from groundbreaking clinical trials using focused ultrasound to enable targeted drug delivery across the BBB for conditions such as pediatric gliomas and breast cancer metastases, as well as insights on liquid biopsy biomarkers.

Discussion highlights:
The Future of Accessible Treatment: Dr. Meng’s perspective on the next decade of innovation, including the potential shift of focused ultrasound procedures from specialized MRI environments to more accessible, bedside settings within standard infusion centers—broadening patient access and improving treatment tolerability.

Center of Excellence (COE): Established as a COE in 2016, the Sunnybrook Health Sciences Centre is conducting research for focused ultrasound in neurology, neurosurgery, urology, orthopedics, gynecology, radiation oncology, and biomedical engineering. The COE program recognizes luminary sites for their excellence in translational and clinical research, training, and patient care.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
19min
April 07, 2026Ep50: Living a Pain-Free Life with Dr. Sanjay Gupta and the Role of Focused Ultrasound with Dr. Lauren Hadley
Chronic pain affects one in five adults, yet it remains a deeply personal and often misunderstood experience. For many, the search for relief becomes a cycle of treatments that fail to deliver lasting results, sometimes leading to long-term reliance on medications that can significantly impact quality of life.
In this special episode of Curing with Sound, we examine the future of pain management from three unique perspectives. We begin with renowned neurosurgeon and CNN Chief Medical Correspondent Sanjay Gupta, MD, who shares insights from his latest book, It Doesn’t Have to Hurt: Your Smart Guide to a Pain-Free Life. Dr. Gupta explores how pain is not merely a physical signal, but a complex experience shaped by the brain and nervous system, one influenced by movement, sleep, stress, and daily interactions.
The episode also features Lauren Hadley, MD, MBA, the Foundation’s Associate Director of the Research and Education Team, who discusses the science behind focused ultrasound as a noninvasive alternative to traditional surgery and pharmacologic treatments.
Finally, we hear from Reginald Masters, a patient whose chronic low back pain was successfully treated with focused ultrasound, offering a compelling firsthand account of life before and after treatment.
Discussion highlights:
The Neuroscience of Pain: Dr. Sanjay Gupta examines the subjective nature of pain, drawing on years of clinical experience and reporting to shed light on how pain is understood and managed.

A Noninvasive Revolution: Dr. Lauren Hadley explains how focused ultrasound is transforming pain treatment by targeting the source through approaches such as thermal ablation and neuromodulation.

A Patient’s Journey to Relief: Reginald Masters shares his experience living with debilitating pain for decades and finding rapid relief through a noninvasive focused ultrasound procedure.
All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.

EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
42min
March 24, 2026Ep49: Breaking Through Treatment Barriers: Focused Ultrasound for Pancreatic Cancer
Pancreatic cancer remains one of the most difficult cancers to treat, largely because its dense tumor microenvironment makes it difficult for chemotherapy drugs to reach their target. This often leads to poor patient outcomes and underscores the urgent need for new therapeutic strategies to overcome these barriers.

In this episode of Curing with Sound, Jae Young Lee, MD, PhD, professor and researcher at Seoul National University Hospital, shares his work exploring focused ultrasound as a noninvasive treatment option for pancreatic cancer. He explains how this technology creates subtle mechanical stress within the tumor, helping to open up its structure so chemotherapy can work more effectively. Dr. Lee also shares encouraging results from his Phase II clinical trial and looks ahead to a pivotal Phase III study, offering new hope for improving patient outcomes.

Discussion highlights:
A New Treatment Strategy: Focused ultrasound technology shows promise for addressing the unique challenges of pancreatic cancer, enabling precise tumor targeting while preserving critical surrounding structures.

From Research to Reality: Learn how Seoul National University Hospital, a designated Focused Ultrasound Center of Excellence, is integrating this technology into clinical care while advancing research across oncology, neurosurgery, and pain management.
Seoul National University Hospital Website
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org
FOCUSED ULTRASOUND TREATMENT SITES
https://www.fusfoundation.org/the-technology/treatment-sites/

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
14min
March 10, 2026Ep48: Finding the Light: A Prostate Cancer Survivor's Experience with Focused Ultrasound
In this episode of Curing with Sound, we speak with Peter Dolan, a lifelong athlete and prostate cancer survivor who chose focused ultrasound after receiving an unexpected diagnosis despite a reassuring MRI. Peter shares his experience navigating treatment decisions and offers a candid account of the outpatient procedure and recovery process. He describes a swift return to his active lifestyle, free from the side effects he had anticipated.
Facing a prostate cancer diagnosis requires careful decisions about treatment and long-term quality of life. Peter’s story underscores the importance of informed, personalized care and illustrates how focused ultrasound may offer effective treatment with fewer lasting impacts on daily life.

Discussion highlights:
An Unexpected Diagnosis: How a routine PSA test led to a prostate cancer diagnosis and why imaging alone did not tell the whole story.

Choosing a Noninvasive Path: Explore the decision-making process behind selecting focused ultrasound over traditional surgery or radiation, and hear a firsthand account of the simple, outpatient procedure.

Life After Treatment: Discover how focused ultrasound provided a swift return to a vibrant, active life without long-term side effects and inspired Peter’s ongoing patient advocacy.
All patient stories featured on the Curing with Sound podcast are personal accounts of an individual’s experience with focused ultrasound treatment. Please be aware that each patient’s situation is unique, and outcomes may vary. The information provided in this story should not be considered as medical advice or a guarantee of specific results. It is important to consult with a qualified healthcare provider to discuss your condition and determine the best treatment options for you. The Focused Ultrasound Foundation does not endorse any specific treatment or medical procedure and encourages all patients to seek professional medical guidance tailored to their individual needs.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
18min
February 17, 2026Ep47: From Bench to Kennel: Advancing Veterinary Medicine with Focused Ultrasound
For pet owners, a diagnosis such as cancer or chronic disease often brings difficult decisions and limited treatment options, many of which involve invasive procedures. While human medicine has advanced significantly, many of these innovations have been slower to reach veterinary care, underscoring the need for more effective and less invasive approaches to animal health.
In this episode of Curing with Sound, we speak with Philip Bergman, DVM, MS, PhD, DACVIM-Oncology, Veterinary Program Director at the Focused Ultrasound Foundation. Dr. Bergman oversees Foundation-funded preclinical research and the clinical studies that enroll companion animals, helping to accelerate translational progress across species.
The conversation explores emerging applications of focused ultrasound in veterinary medicine, including its potential role in treating osteosarcoma, glioblastoma, feline diabetes, and other complex conditions. Dr. Bergman also discusses the collaborative One Medicine approach and how it is advancing care for both animals and people.

Discussion highlights:
One Medicine Revolution: Companion animals naturally develop many of the same diseases as humans, allowing veterinary research to inform human medicine—and vice versa—through a shared, translational approach.

Breakthroughs in Standard of Care: He shares his vision for a “bench-to-bedside-to-kennel” cycle, in which insights from animal clinical trials accelerate human therapies and human breakthroughs inspire new, noninvasive treatment options for pets.

The Future of Veterinary Technology: Hear about efforts to develop cost-effective, veterinary-specific focused ultrasound systems designed to bring this technology into everyday clinical practice.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
20min
January 27, 2026Ep46: Focused Ultrasound and the Future of Cancer Immunotherapy with Natasha Sheybani, PhD
In this episode of Curing with Sound, we speak with Natasha Sheybani, PhD, assistant professor of biomedical engineering at the University of Virginia (UVA) and research director of the UVA Focused Ultrasound Cancer Immunotherapy Center. Dr. Sheybani shares insights into her groundbreaking work using focused ultrasound–based immunotherapy approaches in patients with metastatic breast cancer and other solid tumors.
She explains how precisely delivered sound waves can do more than destroy tumors—helping to reshape the tumor microenvironment, overcome immune evasion, and activate the immune system to recognize and attack cancer cells. The conversation also explores Dr. Sheybani’s strong commitment to mentorship and interdisciplinary training, as well as her efforts to integrate patient advocates directly into the research process.
Discussion Highlights:
Sheybani Lab Research: The lab explores how focused ultrasound can help activate the immune system and improve the delivery of immunotherapy drugs to solid tumors, including brain cancers such as glioblastoma and metastatic breast cancer.

Era of Hope Scholar Award: Learn about the prestigious $5.5 million Department of Defense grant awarded to Dr. Sheybani—the first ever at UVA—to accelerate the development of focused ultrasound technologies that improve the safety, effectiveness, and precision of immunotherapy for patients with breast cancer.

Patient-Centered Science: Hear how Dr. Sheybani is redefining the research process by integrating breast cancer survivors directly into her grant writing and experimental design, fostering scientific innovation that is deeply informed by real-world patient experience.
EPISODE TRANSCRIPT
----------------------------

QUESTIONS?
Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances.
Email [email protected] if you have questions about focused ultrasound or the Foundation.
FUSF SOCIAL MEDIA
LinkedIn
X
Facebook
Instagram
TikTok
YouTube
FUSF WEBSITE
https://www.fusfoundation.org

SIGN UP FOR OUR FREE NEWSLETTER
https://www.fusfoundation.org/newsletter-signup/

READ THE LATEST NEWSLETTER
https://www.fusfoundation.org/the-foundation/news-media/newsletter/

DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK)
https://www.fusfoundation.org/read-the-tumor-by-john-grisham/
...more
25min

FAQs about Curing with Sound:

How many episodes does Curing with Sound have?

The podcast currently has 56 episodes available.