Klara Nahrstedt, a professor of computer science and director of the Coordinated Science Laboratory at the University of Illinois, discusses her involvement in several National Science Foundation and Department of Energy cyber infrastructure projects. Those include building advanced real-time security in cyber-physical systems (smart grid and electric vehicles) and secure sensor networks monitoring of oil and gas cyber-physical infrastructure. She also touches on quality of service management in multimedia networks and its implications on Net Neutrality.