The Chemical Collective discusses Datura, a nightshade plant known for its hallucinogenic and deliriant properties. Datura species include Jimsonweed, Moonflower, and Devil's Trumpet, with large, fragrant flowers and spiky seed pods. Historically used in the American Southwest and globally for medicinal, spiritual, and recreational purposes, Datura contains tropane alkaloids like scopolamine, atropine, and hyoscyamine, which disrupt acetylcholine receptors, causing hallucinations, confusion, and potentially fatal side effects. Despite some medicinal uses, Datura's unpredictable potency and severe risks make it highly dangerous and not suitable for self-medication.