Please visit answersincme.com/YYB860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in ophthalmology discusses strategies for selecting anti-VEGF therapy and maintaining adherence for patients with diabetic macular edema. Upon completion of this activity, participants should be better able to: Describe guideline-concordant, evidence-based strategies to select appropriate therapy for patients with diabetic macular edema (DME); Review the clinical profiles of longer-acting vascular endothelial growth factor (VEGF)-targeted agents with phase 3 trial evidence in the treatment of DME; and Outline patient-centered management approaches to improve adherence to VEGF-targeted therapy.