David Sable got his start in reproductive medicine in the late 1980s, a time when he says fertility treatments were "very primitive." But by the mid-2000s, he says, new procedures and new insights into the genetics of development had changed everything. His subsequent time observing (and investing in) the field has convinced him that reproductive medicine is "the most interesting area of medicine this century."

Sable is a medical and entrepreneurial chameleon who trained in obstetrics and gynecology, worked as a reproductive endocrinologist, co-founded the Institute for Reproductive Medicine and Science fertility clinic, co-founded the embryo genetic testing firm Reprogenetics, and now works as portfolio manager of the Special Situations Life Sciences Fund and the Life Sciences Innovation Fund while also writing for Forbes and teaching biotech entrepreneurship at Columbia University. 

Intriguingly, Sable says his earliest inspiration to become a medical entrepreneur came from the brief scene at the end of The Empire Strikes Back in which a robot clinician gives Luke Skywalker a prosthetic hand. To Sable, the seeming everydayness of the operation spoke to the possibility of "taking the miraculous and turning it into the mundane—taking the medicine and the science and along the way adding a lot of engineering to it."

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