Prescribing is one of the most powerful — and most perilous — acts in medicine. This chapter explores how treatments are chosen, adjusted, and monitored, and why good prescribing is less about knowing drugs than about understanding people, physiology, and context.

In this audio deep dive, we examine how medicines work in real bodies rather than idealised ones. You’ll hear how pharmacokinetics and pharmacodynamics translate into day-to-day decisions, why therapeutic ranges are guides rather than guarantees, and how harm often emerges at the edges of good intention.

This chapter reframes prescribing as a craft: one that requires precision, restraint, and continual reassessment. It reminds us that every prescription is a hypothesis — and every follow-up, a test.

This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit drmanaankarray.substack.com/subscribe