In Episode 22, we’re diving into Immunology with a practical, clinic-ready breakdown of BMS (blistering mucosal syndromes) and other chronic blistering dermatoses. We connect the “why” (autoantibodies, target antigens, inflammation pathways) to the “what you do next” (how they present, how to confirm the diagnosis, and how to treat effectively without overcomplicating the workup).

You’ll get a clear framework for differentiating common blistering disorders, choosing the right tests (and biopsy technique), interpreting immunofluorescence patterns, and building treatment plans that balance speed of control, safety, and long-term maintenance. We also cover newer FDA-approved options and evolving therapeutic strategies, including where they fit in your step-up/step-down approach and which patients may benefit most.