In this episode of the Ingredientsage Podcast, we take a clear, evidence-based journey into how dietary supplements are legally classified and regulated in the United States.

From DSHEA to FDA oversight, we break down the rules that govern manufacturing, labeling, claims, and marketability—giving both consumers and brand owners the clarity they need to navigate this complex space.

You’ll learn how supplements differ from foods, OTC drugs, and cosmetics; what “structure/function” claims really mean; how New Dietary Ingredients (NDIs) are evaluated; and what responsibilities manufacturers and private label brands hold when bringing a product to market. We also explore common regulatory pitfalls, including mislabeling, improper claims, and GMP violations, and explain how to avoid them.

Whether you’re building a supplement brand or simply trying to understand the safety systems behind the products you take, this episode provides a grounded, insider-informed view of the regulatory landscape.

Because understanding ingredients is the first step toward building better wellness.