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Diphenhydramine
Trade NameBenadryl
IndicationAllergy, anaphylaxis, sedation, motion sickness, antitussive
ActionAntagonizes effects of histamine, CNS depression
Therapeutic ClassAllergy, cold and cough remedy, antihistamine, antitussive
Pharmacologic ClassAntihistamine
Nursing Considerations• May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache • Anticholinergic effects (dry mouth, blurred vision, constipation, sedation) • Assess purpose of medication prior to giving it • Assess allergies, sleep patterns, cough and lung sounds • Patient should avoid other over-the-counter cough and cold remedies
By Jon Haws, RN CCRN Alumnus4.4
157157 ratings
Diphenhydramine
Trade NameBenadryl
IndicationAllergy, anaphylaxis, sedation, motion sickness, antitussive
ActionAntagonizes effects of histamine, CNS depression
Therapeutic ClassAllergy, cold and cough remedy, antihistamine, antitussive
Pharmacologic ClassAntihistamine
Nursing Considerations• May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache • Anticholinergic effects (dry mouth, blurred vision, constipation, sedation) • Assess purpose of medication prior to giving it • Assess allergies, sleep patterns, cough and lung sounds • Patient should avoid other over-the-counter cough and cold remedies

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