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Discovery and biosynthesis of clostyrylpyrones from the obligate an-aerobe Clostridium roseum
Link to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.08.10.245514v1?rss=1
Authors: Li, J. S., Du, Y., Gu, D., Cai, W., Green, A., Ng, S., Leung, A., Zhang, W.
Abstract:
Anaerobic bacteria are a promising new source for natural product discovery. Examination of extracts from the obligate an-aerobe Clostridium roseum led to discovery of a new family of natural products, the clostyrylpyrones. The polyketide synthase-based biosynthetic mechanism of clostyrylpyrones is further proposed based on bioinformatic, gene knockout and heterologous expression studies.
Copy rights belong to original authors. Visit the link for more info
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By Multimodal LLCLink to bioRxiv paper:
http://biorxiv.org/cgi/content/short/2020.08.10.245514v1?rss=1
Authors: Li, J. S., Du, Y., Gu, D., Cai, W., Green, A., Ng, S., Leung, A., Zhang, W.
Abstract:
Anaerobic bacteria are a promising new source for natural product discovery. Examination of extracts from the obligate an-aerobe Clostridium roseum led to discovery of a new family of natural products, the clostyrylpyrones. The polyketide synthase-based biosynthetic mechanism of clostyrylpyrones is further proposed based on bioinformatic, gene knockout and heterologous expression studies.
Copy rights belong to original authors. Visit the link for more info