The results of the SYNTAX trial have been hotly debated since they were first presented. The recent analysis of costs and quality-of-life outcomes, presented at the ACC 2009 Scientific Sessions, suggests that CABG-treated patients have more angina relief at one year but that PCI is the more cost-effective strategy, at least in low- and moderate-risk patients. During the first month, quality-of-life analyses clearly favor PCI, but these differences evaporate over the first year. In higher-risk patients, CABG was the clear winner when both costs and lifestyle issues are considered.

Join Drs Robert Harrington, Sanjay Kaul, and Harlan Krumholz for a frank and detailed discussion on the SYNTAX trial, how it has changed what happens in the cath lab, and if and how it should affect guidelines.

In Part 2 of the program, the JUPITER trial is back on the table and our experts give their opinion on the polypill following the results of the TIPS study.