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We walk through how to distinguish delirium from encephalopathy using DSM-5 criteria, CAM tools, and clear coding pathways, and we show where they overlap and why it matters. We share practical examples, denial risks, and how nurses’ notes fuel better queries and outcomes.

• DSM-5 features and CAM thresholds for delirium
• F-code specificity for intoxication and withdrawal states
• G-code encephalopathy and system-specific hepatic coding
• Overlap of causes and resolution with treatment
• Differentiating waxing and waning vs acute course
• CC/MCC, Elixhauser, PSI 11 and denial risk
• Using nurses’ notes to build strong queries
• Key resources for fast, reliable criteria checks

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