We are beings who wield both creation and destruction, and both of these are a part of all existence.
We know practically nothing. But if we wish to become wise, we must work towards that goal, knowing that perhaps it is an impossible one.
And we learn that the choice to do so is meaningful, and gives our life direction and purpose. As do all conscious choices that we make.
We can choose to create, or to destroy. And those acts, freely chosen, are more meaningful than the ones that happen arbitrarily.