Genai Coleman was a Houston woman convicted in 2003 for the murder of her ex-girlfriend, but her case drew attention because of a complicated DNA twist involving identical twins.

The crime involved the fatal stabbing of her former partner, and investigators found male DNA at the scene. Initially, this confused the case—until it was revealed that Genai had recently been in contact with identical twin brothers, and DNA evidence alone couldn't distinguish between them, since identical twins have nearly identical genetic profiles.

This case highlights a rare challenge in forensic science: DNA can't tell identical twins apart using standard testing, which can complicate investigations when either or both twins could be suspects. Although Genai Coleman was ultimately convicted, her case is often cited in legal and scientific discussions about the limitations of DNA evidence when it comes to identical twins and complex crime scenes.