In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a step back from the hype surrounding cutting-edge longevity supplements to ask a more practical — and important — question: Do you really need expensive, trendy longevity products to support healthy aging?

With longevity now dominating wellness headlines, many supplements promise to slow aging, lengthen telomeres, boost NAD+, or activate autophagy — often at a steep monthly cost and with limited long-term human research. Carl explains why longevity isn’t driven by a single “magic molecule,” but by a network of systems including a healthy inflammation response, oxidative stress protection, cardiovascular health, immune system regulation, brain function, and cellular integrity.

In this episode, Carl breaks down how well-established nutrients — backed by decades of human research — already support many of the same biological pathways targeted by newer longevity compounds. He highlights three foundational supplements that almost everyone should prioritize first for both health span and longevity:

• Vitamin D (especially when paired with Vitamin K2)
• Omega-3 fatty acids from high-quality fish oil
• Vitamin E tocotrienols

Carl explains how these nutrients support the same health systems targeted by newer longevity compounds, and even mitochondrial function and  telomere integrity too — all without the uncertainty and cost of newer longevity “stacks.”

You’ll also learn why optimizing the fundamentals can deliver powerful aging benefits today, not just theoretical lifespan gains decades from now.

If you’re curious about longevity but want science-backed, realistic guidance before spending hundreds of dollars a month on supplements, this episode is for you.

WHAT YOU’LL LEARN

• Why longevity isn’t controlled by one single nutrient or pathway
• The hidden downside of expensive, cutting-edge longevity supplements
• Network of systems that influence aging
• Why Vitamin D is one of the most underestimated longevity nutrients
• The role Vitamin K2 plays alongside Vitamin D
• Why omega-3s are often called the “original longevity supplement”
• How omega-3s support heart health, brain health, and telomeres
• What tocotrienols are — and why most vitamin E supplements miss them
• How tocotrienols support cellular, mitochondrial, and brain health
• What telomeres really are and how you can protect them
• Why consistency beats novelty when it comes to healthy aging

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