ATTR-CM is the zebra hiding among the horses. AI may finally be the tool that finds it. Experts Drs Kevin Alexander and Lily Stern explore what's working, what's not, and what comes next.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/ca8/p04/podcast-attr-cm-s1-ep3-2026a10006hb. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Transthyretin-Related Amyloidosis https://emedicine.medscape.com/article/335301-overview

The Role of Artificial Intelligence in Cardiac Amyloidosis: A Focus on Diagnosis and Clinical Application https://pubmed.ncbi.nlm.nih.gov/40558656/

Concordance of Left Ventricular Volumes and Function Measurements Between Two Human Readers, a Fully Automated AI Algorithm, and the 3D Heart Model https://pubmed.ncbi.nlm.nih.gov/39081366/

High-Throughput Precision Phenotyping of Left Ventricular Hypertrophy With Cardiovascular Deep Learning https://pubmed.ncbi.nlm.nih.gov/35195663/

Eplontersen for Hereditary Transthyretin Amyloidosis With Polyneuropathy https://pubmed.ncbi.nlm.nih.gov/37768671/

Diagnosing AL and ATTR Amyloid Cardiomyopathy: A Multidisciplinary Approach https://pubmed.ncbi.nlm.nih.gov/39407933/

Advances in Imaging-Based Diagnosis, Prognosis, and Response Assessment in Cardiac Amyloidosis: A Comprehensive Multimodality Review https://pmc.ncbi.nlm.nih.gov/articles/PMC12450123/

Exploring the Utility of Carpal Tunnel Biopsy in Amyloidosis: A Current Perspective https://pubmed.ncbi.nlm.nih.gov/39588898/

Design and Rationale the SCAN-MP (Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations) Study https://pubmed.ncbi.nlm.nih.gov/37066788/

Artificial Intelligence-Enhanced Electrocardiogram for the Early Detection of Cardiac Amyloidosis https://pubmed.ncbi.nlm.nih.gov/34218880/

Machine Learning-Based CT Angiography-Derived Fractional Flow Reserve for Diagnosis of Functionally Significant Coronary Artery Disease https://pubmed.ncbi.nlm.nih.gov/36889853/

NYHA Classification for Decision-Making in Heart Failure: Time to Reassess? https://pubmed.ncbi.nlm.nih.gov/37264724/

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