We begin this episode by having Dr. Dinler Antunes explain what cancer immunotherapy is. Dr. Antunes gives an extremely thorough, clear explanation of what cancer immunotherapy is, how it works, and the many concepts involved. These concepts include how the human immune system works and how peptides are displayed on the outside of cancer cells. Further topics include how cancer cells can be differentiated from normal cells and the different types of immunotherapy possibilities that arise as a result. We then learn about some of Dr. Antunes own work, such as the HLA-Arena software package (see more at https://dinlerantunes.com/). Finally, we discuss the future promise and potential hurdles of cancer immunotherapy.