In today’s episode, Evgeny Lebedev talks about the remarkable potential of ketamine with Dr John Krystal, Professor of neuroscience at the Yale School of Medicine. 

Their discussion delves into the world of neurology, what ketamine actually does to our brain and the importance of glutamate receptors in treating depression. Ketamine may have gotten bad press after Friends actor Matthew Perry died of an overdose while receiving treatment with the drug, but for Dr Krystal, it is a critically overlooked solution to the epidemic of mental illness.

Also in this episode:

• Ketamine’s complicated history starting in the 1950s
• The real reason depression leads to suicide
• Why ketamine is effective at dealing with trauma
• The detailed procedure of ketamine therapy 
• The importance of ketamine’s “narrow window” dosage
• Ketamine’s reputation and why it needs to change

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