What if we could detect endocrine resistance before it shows up on scans?

In this CHM Conversations episode, Dr. Sigrun Hallmeyer and Dr. William Gradishar break down the SERENA-6 trial and what it means for the future of HR-positive, HER2-negative metastatic breast cancer.

From early detection of ESR1 mutations using ctDNA to switching therapy before clinical progression, this discussion explores how molecular monitoring is reshaping treatment decisions, extending progression-free survival, and preserving quality of life.

The conversation also dives into real-world implementation, patient experience, cost considerations, and what comes next as oncology moves toward more personalized, biology-driven care.

A must-watch for clinicians navigating the evolving endocrine landscape.

🎧 Watch more expert-led oncology conversations from CHM Conversations.

#BreastCancer #HRPositive #Oncology #ESR1 #ctDNA #SERENA6 #EndocrineTherapy #MedicalOncology #PrecisionOncology #CommunityHealthMedia

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