The MaML Podcast - Medicine & Machine Learning

Dr. Steven Hart - From factory worker to leader in AI and Digital Pathology at Mayo Clinic


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Dr. Steven Hart is a Senior Associate Consultant in AI at Mayo Clinic who has played a key role in shaping genomics and digital pathology with GenomeGPS, Mayo Clinic’s primary DNA sequencing workflow. His groundbreaking contributions have led to advancements in understanding inherited cancer risk and improving digital pathology workflows. With over 100 peer-reviewed publications, Dr. Hart’s innovative algorithms are driving efficiency in genetic predisposition testing, reducing unnecessary procedures, and enhancing precision healthcare.


We had some audio issues for this one which we tried to fix but they're still pretty apparent so apologies for that D:!


00:00:00 - Introduction 

00:01:09 - From a factory worker to a leader in AI and medicine

00:05:11 - Proving people wrong as a motivator

00:06:37 - Crazy factory stories

00:07:38 - Why Mayo Clinic?

00:09:52 - Surprising things about Mayo Clinic

00:11:33 - Is Mayo Clinic’s data high quality?

00:12:55 - How to prepare healthcare for AI (and why AI won’t actually have the biggest impact)

00:20:50 - Democratizing pathology with AI 

00:25:38 - Will AI replace pathologists?

00:29:24 - How do you judge how well an embedding works? 

00:33:22 - Reducing expectations for diagnostic AI usage in healthcare

00:36:46 - How do you keep up with the rapidly evolving pace of AI?

00:38:31 - OpenAI o1 and prompt hacking 

00:41:27 - Are we close to artificial general intelligence? 

00:47:03 - How helpful are regulatory agencies like the FDA with translating AI?

00:49:52 - What makes a good question?

00:53:33 - Favorite parts about living in Rochester, MN

00:55:14 - What gives your life meaning? 

00:58:36 - Advice for young people in uncertain times


Host: Nathan Keller

Twitter: @NathanKellerX

Linkedin: https://www.linkedin.com/in/nathankeller1/


Producer: Saurin Kantesaria

Linkedin: Saurin Kantesaria




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The MaML Podcast - Medicine & Machine LearningBy Twitter - @themamlpodcast | TikTok - @maml_podcast

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