February 02, 2026

E18 - Multi-Target Radiotherapy Conformity Index

11 minutes

E18 | 12 min | Latest | Publication Link

Podcast based on: Sang, Y.; Dang, J.; Wu, J.; Wu, Y.; Quan, E.; Dai, J. Generalization of the Conformity Index for Multi-Target Radiotherapy Plans. Cancers 2026, 18, 426. https://doi.org/10.3390/cancers18030426

Type: Article | Publication date: 28 January 2026

Summary: This study proposes a generalized method to calculate the Conformity Index (CI) for multi-target radiotherapy plans (e.g., breast or nasopharyngeal cancer). Standard CI formulas are often distorted in these complex scenarios because they erroneously include dose spillover from adjacent targets. To address this, we redefined the Target Volume (VTV) parameter to mathematically isolate the prescription dose region of each specific target. Validation on clinical plans demonstrated that the new formula effectively eliminates interference from neighboring targets, providing CI values that accurately reflect the true dose conformity. This improved calculation is recommended for the objective evaluation of multi-target radiotherapy plans.

Keywords: radiotherapy planning; generalized conformity index; evaluation; multi-target plans

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