Sinapsos Podcast | Oncology

E24 - ABHD5 in Cancer Research Progress

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E24   |  13 min   |   Latest   |  Publication Link

  • Podcast based on: Cai, H.; Chen, H.; Ye, J.; Jin, Z.; Huang, P. Current Research Progress on ABHD5 in Cancers. Cancers 2026, 18, 585. https://doi.org/10.3390/cancers18040585
    • Type: Review  |  Publication date: 10 February 2026

  • Summary: ABHD5 is a key regulator of lipid metabolism, with context-dependent roles in cancer. It interacts with signaling pathways like AMPK/mTOR, AKT, and NF-κB, exerting either tumor-suppressive or oncogenic effects based on the tumor’s ecological and molecular context. This review synthesizes experimental and clinical evidence to clarify its multifaceted functions and explores its potential as a diagnostic marker and therapeutic target, emphasizing the need for precision strategies rather than blunt intervention.

  • Keywords: ABHD5; lipid metabolism; cancer; pathway

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    Disclaimer:

    This podcast provides a synthetically generated voice summary and discussion of scientific publications. The views expressed do not represent the views of the original authors, journals, or publishers. This podcast uses AI-assisted summaries, so it may or may not introduce inaccuracies or omit important details. Listeners are strongly encouraged to consult the original publications or sources for full context and accuracy. This podcast is for educational and informational purposes only and does not constitute clinical advice, medical guidance, or recommendations. The creators of this podcast are not liable for any errors, omissions, or outcomes resulting from the use of the information provided.

     

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