In 2003, the first whole human genome sequencing cost totalled to roughly $2.7 billion. With rapid advancements in new tools, research and sequencing technologies, a new wave of techies is on the rise taking engineering principles to the biological domain. In this cast we talk to one such Co-Founder, Zack Abbott, about the rise of Synthetic Biology, his company, ZBiotics, and their work to build a probiotic product to alleviate hangovers.