January 08, 2026

E3 - MRI for Ovarian Cancer Peritoneal Disease Resectability

9 minutes

E3 | 10 min | Latest | Publication Link

Podcast based on: Konidari, M.; Gourtsoyianni, S.; Thomakos, N.; Lymperopoulou, G.; Tzavara, C.; Pergialiotis, V.; Rodolakis, A.; Moulopoulos, L.A.; Bourgioti, C. Prediction of Resectability of Peritoneal Disease in Ovarian Cancer Patients Using the Peritoneal Cancer Index (PCI) and Fagotti Score on MRI. Cancers 2026, 18, 165. https://doi.org/10.3390/cancers18010165

Type: Article | Publication date: 02 January 2026

Summary: Optimal cytoreduction is the strongest prognostic factor in ovarian cancer presenting with peritoneal disease. However, selecting patients for primary cytoreductive surgery versus neoadjuvant chemotherapy remains challenging. In this study, we evaluated the prognostic performance of MRI-based Fagotti score and Peritoneal Cancer Index (PCI) in women with ovarian cancer. Both MRI-based Fagotti score and PCI demonstrated high accuracy for predicting surgical feasibility, with optimal cut-offs (Fagotti ≤ 6, PCI ≤ 20) strongly associated with optimal cytoreduction. These findings suggest that MRI-based scores can serve as an alternative noninvasive tool for guiding treatment decisions and surgical planning in ovarian cancer patients.

Keywords: ovarian cancer; MRI; peritoneal carcinomatosis; cytoreduction; Peritoneal Cancer Index; Fagotti score; Diffusion-Weighted Imaging

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