The AI Cookbook with Malcolm Werchota

E36: Patients First? Why Pharma Sleeping on GenAI Costs Lives


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The most uncomfortable 20 minutes in pharma this year: How GenAI achieves 90% drug discovery success while you're at 0.01%.

Verified facts from yesterday's Nature paper and last week's industry announcements.

Breaking down:

  • 8 successful cancer drug candidates from 9 attempts (published yesterday, peer-reviewed)
  • Traditional Phase 2 success: 28-40% | AI-enhanced: 89% (CDK2 target Pfizer couldn't crack)
  • 1 billion molecular evaluations per week vs your 1,000 per year
  • "Novel scaffolds": How AI generates entirely new patent families (20-year monopolies)
  • The companies already shipping: Atomwise, BenevolentAI, Recursion (with Phase 2 proof)
  • Why "it's not our core competency" is a death sentence for your pipeline

Plus: The 6-month committee meeting that costs 500 cancer patients their lives.

Every day you "observe further" is a day your competitors get closer to making you obsolete.

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The AI Cookbook with Malcolm WerchotaBy Malcolm Werchota