In this episode of The Connected Physician, host Katharina Juenger welcomes Ryan Fukushima, co-founder and former COO of Tempus and founding CEO of Pathos AI. As a trailblazer in healthcare AI, Ryan shares his remarkable journey—from building one of the largest next-generation sequencing labs in the U.S. to launching a drug development company that’s raised over $100M.

Katharina and Ryan explore how AI and big data are revolutionizing healthcare—from streamlining clinical workflows to redesigning the future of clinical trials. Ryan sheds light on the real-world impact of Tempus' "smart tests," the role of AI copilots like Tempus One, and why physicians who embrace AI will thrive in the evolving medical landscape.

In this episode, Katharina and Ryan discuss:

✅Solving Data Fragmentation in Oncology – How Tempus integrates EMR, lab results, imaging, and clinical notes to deliver a complete patient picture.

✅Smart Tests for Smarter Treatment – The value of combining test results with patient history to guide clinical decisions and trial options.

✅Tempus One: The AI Copilot for Oncologists – A ChatGPT-style assistant that knows your patient’s history and works within EMRs to optimize care.

✅Pathos AI and the Future of Drug Development – How focused AI and biomarker-driven trials can speed up drug discovery with higher success rates.

✅Digital Twins in Clinical Trials – Using AI to ethically and efficiently replace control groups, especially in oncology.

✅AI as an Accelerator, Not a Replacement – The balance between automation and essential human judgment in diagnostics and decision-making.

✅The Physician’s Evolving Role in an AI-Enabled World – Why AI won’t replace doctors—but will redefine their value.

✅Education, Creativity, and the Next Generation – Preparing for a future where AI is a native tool for solving complex human problems.

Ryan also shares his optimism for the future—one where AI empowers both physicians and patients, accelerates meaningful therapies, and unlocks new human potential.

Tune in to learn how AI is not only reshaping the future of healthcare but also redefining what it means to be a connected physician.

Links and Resources: Ryan Fukushima on LinkedIn - https://www.linkedin.com/in/ryanfukushima/

This podcast is brought to you by Cade Partners—helping private practices grow. If your practice generates over $10M in revenue and you're seeking capital and support to scale, reach out at https://www.cadepartners.com/connect

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