Exposure of blood plasma/serum (P/S) to thawed conditions (> -30 °C) can produce biomolecular changes that skew measurements of biomarkers within archived patient samples, potentially rendering them unfit for molecular analysis.  Since freeze-thaw histories are often poorly documented, objective methods for assessing molecular fitness prior to analysis are needed.

Exposure of blood plasma/serum (P/S) to thawed conditions (> -30 °C) can produce biomolecular changes that skew measurements of biomarkers within archived patient samples, potentially rendering them unfit for molecular analysis. Since freeze-thaw histories are often poorly documented, objective methods for assessing molecular fitness prior to analysis are needed.

Exposure of blood plasma/serum (P/S) to thawed conditions (&gt; -30 °C) can produce biomolecular changes that skew measurements of biomarkers within archived patient samples, potentially rendering them unfit for molecular analysis.  Since freeze-thaw histories are often poorly documented, objective methods for assessing molecular fitness prior to analysis are needed.

Empirically tracking the exposure of human plasma & serum samples to thawed conditions

What's happening in the clinical lab community including publications in JMSACL and interviews with the Early Career Network.

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Empirically tracking the exposure of human plasma & serum samples to thawed conditions

Empirically tracking the exposure of human plasma & serum samples to thawed conditions