107. Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness Protocol

How can mushrooms sync with your cycle—or shift your experience of menopause? In this episode, April Pride is joined by Jennifer Chesak, author of The Psilocybin Handbook for Women, to decode the powerful relationship between psilocybin and women’s hormones. Together, they explore the latest research, ancestral wisdom, and practical strategies for using psychedelics across different phases of a woman’s life. From syncing mushroom journeys with ovulation to microdosing through perimenopause, this conversation empowers women to tailor their approach to their unique physiology. Expect science, storytelling, and no-BS protocol advice grounded in lived experience.

🔵 Key Takeaways

-Psilocybin affects the menstrual cycle via the stress-regulating HPA axis, with possible benefits like cycle regulation or early onset.

-Optimal time to journey is near ovulation, when energy and estrogen levels support a deeper experience.

-Indigenous wisdom aligns with new science, reinforcing cycle-aware practices for safe, intentional use.

-Psilocybin can support perimenopause by easing depression, improving libido, and helping resolve trauma.

-A microdosing protocol should be personal—guided by intuition, not rules made by men.

Learn more about this episode, including guests and resources on substack:https://aprilpride.substack.com/p/psilocybin-menstrual-cycles-menopause

Hosted by April Pride

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