In the third episode of our "Interesting Stories in the History of Diagnostics" series, Dr. Mickey Urdea expounds on the history of diseases caused by helminths - aka parasitic worms! Helminth diseases still affect more than 1.5 billion people worldwide (24% of the world's population!) today, and properly testing for the presence of worms is a challenge that the diagnostics industry continues to master. From being the subject of Charles Darwin's best-selling book (really!) to being the impetus for the founding of the Rockefeller Foundation, worms have had a surprisingly significant effect on diagnostics history.