The series follows the adventures of a team of scientists on the Calico, a hydrofoil research vessel, headed by Captain Carl Majors. The rest of the crew include scientist Dr. Quinn Darien, her nephew Pete, her research assistant Brock, and the ship's first mate, Carl. Also along for the ride is Godzuki, the "cowardly cousin" of Godzilla and Pete's best friend, who has a lighthearted role in the show. The group often call upon Godzilla by using a special communicator when in peril, such as attacks by other giant monsters.