Conphidance earned an Independent Spirit Award nomination for Best Male Performance in a New Scripted Series for his starring role on Little America - Little America: The Cowboy (2020). As the star and face of the anthology series season one, Little America (2020), Conphidance garnered high praises from Rolling Stone, Variety, Deadline, The Guardian, IndieWire, Past Magazine and The Washington Post.

Conphidance can be seen in CBS comedy, Bob Hearts Abishola (2019), opposite Billy Gardell and Folake Olowofoyeku, the Golden Globe and Emmy Awards winning Atlanta (2016), opposite Donald Glover and Zazie Beetz, Emmy Nominated American Gods (2017) opposite Orlando Jones and in Complications (2015) created by Matt Nix. Additional works include Fist Fight (2017), opposite Ice Cube, The Sacrament (2013), Valor (2017), Survivor's Remorse (2014), Six (2017), and the Daytime Emmy Award winning The Inspectors (2015).

Additionally, Conphidance has worked as a musician in films and TV shows, including Constantine (2014). Over the years, he has also worked on commercials and industrials across the U.S and oversees. His most notable theatrical performance was playing Joseph Asagai in "A Raisin in the Sun."