When the gods take with one hand, they give with the other. Over the years, the Good Queen Alysanne would be blessed with many more children. But at the same time, tragedies would strike as she would lose a few children as well, due to disease and other complications. The realm, although otherwise prosperous under the good rule of Jaehaerys, would be struck with an unusually cold winter and a pandemic called the Shivers. The wheel of fortune turns, and there's no way for even House Targaryen, as powerful as they are, to escape the whims of fortune.