In this episode of Everyday Medicine, Christopher Chiu is joined by clinical pharmacist Lindsey Lee, who provides an in-depth overview of PrEP (Pre-Exposure Prophylaxis), its effectiveness in preventing HIV, the populations that should be considered for PrEP, and the disparities in its usage. They discuss various PrEP medications, including oral options like Truvada and Descovy, and the injectable Apretude, addressing their indications, side effects, and monitoring requirements. Lee also talks about prescribing practices, counseling patients, and ensuring adherence to PrEP regimens, as well as resources for patients who face financial barriers to accessing PrEP. The episode highlights the importance of primary care physicians in managing and discussing PrEP with eligible patients.

00:00 Introduction to Everyday Medicine

00:53 Guest Introduction: Pharmacist Lindsey Lee

01:10 Understanding PrEP Therapy

01:34 Who Should Consider PrEP?

04:30 Oral Medications for PrEP

06:34 Injectable PrEP: Apretude

08:06 Baseline Labs and Monitoring

10:04 Counseling Patients on PrEP

15:11 Intermittent PrEP: The 2-1-1 Method

18:04 Affordability and Assistance Programs

19:03 Conclusion and Final Thoughts