In episode 15 Gabor and I review two studies looking at liver health by linking the process of de novo lipogenesis, with the activity of mTORC2, ChREBP-β and SREBP1c.

Episode 15 - how do mTORC2 and ChREBP-β keep the fat cycle going?

Raphael Sirtoli is the co-founder of www.breaknutrition.com and hosts the Break Nutrition podcast to take a deep dive into the science behind nutrition and medical studies. He’s joined by recurring co-host Gabor Erdosi - the ‘adipocyte Jedi’ of the Lower Insulin Facebook group - to review papers exploring what causes diabetes, obesity and other metabolic disorders. Raphael also interviews a broad range of people, like researchers, engineers, doctors, nurses, philosophers and people with inspiring personal health transformations. The underlying theme of the show is identifying diet and healthy lifestyle myths, breaking them apart and replacing them with up to date science. If you want to understand why the world of nutrition science is filled with contradictions and controversy, you’ve come to the right place. One week you might hear about a doctor’s experience treating diabetics and the next week, what the chairman of NASA’s Advisory Council has to say about the latest scientific studies on ketogenic diets for athletic performance! Raphael’s passion for science communication and good fortune to have smart people speak with him publicly largely stems from him being a long-time podcast aficionado. The health and science podcast he recommends are Robb Wolf’s The Paleo Solution, Richard Morris and Carl Franklin’s 2 Keto Dudes, Rhonda Patrick’s Found My Fitness, Shawn Baker and Zach Bitter’s Human Performance Outliers, Christopher Kelly and Dr.Tommy Wood’s Nourish Balance Thrive, Chris Kresser’s Revolution Health Radio, Dawn Kernagis and Dr.Ford’s STEM-Talk, Jessie Lawler’s Smart Drug Smarts, Joe Rogan’s The Joe Rogan Experience, Dr.Attia’s The Drive, Dan Pardi’s HumanOS Radio and lastly Dr.Limanksy and Jimmy Moore’s The KetoHacking MD.

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Episode 15 - how do mTORC2 and ChREBP-β keep the fat cycle going?

Episode 15 - how do mTORC2 and ChREBP-β keep the fat cycle going?