Clinical trials are a cornerstone of advancing medical knowledge, yet significant disparities remain in how research is conducted globally. Dr. Nitya Wadhwa, a pediatrician and physician–scientist, shares her journey from clinician to investigator. She joins Better Together to discuss the process of conducting multi-country clinical trials including design, getting ethical approvals, data collection, analysis, and dissemination. She shares best practices of harmonization, monitoring, and data safety that ensure high-quality rigorous scientific findings that will impact clinical care, leading to improved health outcomes for children and mothers in low-and middle-income countries.