Radiology Advances Podcast | RSNA

Episode 16: Differentiating cysts from solid masses more reliably on breast ultrasound


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This episode explores a technological advance from Johns Hopkins in the United States that improves diagnostic ultrasound for breast masses. By combining short-lag spatial coherence imaging with an objective metric called generalized contrast-to-noise ratio, the researchers achieved a dramatic boost in diagnostic accuracy—especially in dense breast tissue—while reducing variability among radiologists and avoiding misclassification of cancers.

Generalized contrast-to-noise ratio applied to short-lag spatial coherence ultrasound differentiates breast cysts from solid masses. Sharma et al. Radiology Advances, 2025, 2(6), umaf037.

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Radiology Advances Podcast | RSNABy The Radiological Society of North America