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Episode snapshot

Functional medicine isn’t “woo”—it’s a systems-level approach that treats root causes, not just symptoms. In this replay, Greg Shindler (aka “The Longevity CEO”) joins Alicia and George to reframe health like a business: set a vision, hire the right team, track the right KPIs, and iterate. We get practical on labs and wearables, epigenetic clocks (Horvath, GrimAge, DunedinPACE), peptides and where they do—and don’t—fit, why inflammation is the common denominator, and how to extend healthspan (the years you feel strong, clear, and mobile), not just lifespan.

 Programming note: Greg discusses plans for a Los Cabos clinic during this conversation; that location did not open.

Key takeaways

• Be the CEO of your health. Define a vision, assemble specialists, and review objective data regularly.
• Functional medicine = root-cause care. Broader labs (100+ biomarkers), quality supplementation, and personalized protocols.
• Measure what matters. Beyond weight and BP: metabolic and lipid panels, sleep, HRV, strength, and epigenetic clocks—especially DunedinPACE for 8–12 week changes.
• Peptides aren’t a magic button. They can be helpful after foundations (sleep, nutrition, training, stress) are solid.
• Inflammation is the through-line. Most choices either add to or reduce systemic inflammation.

Action plan (start this week)

1. Book a functional medicine intake. Bring your latest labs; ask for a comprehensive panel (100+ biomarkers) and a DunedinPACE test where available.
2. Define your vision & KPIs. Example: “Deadlift bodyweight x5, 7–8 hrs sleep avg, HRV > 60, walking 8–10k/day.” Review every 8–12 weeks.
3. Lock the four foundations.
   • Sleep: consistent schedule; track time asleep and efficiency.
   • Nutrition: protein target, fiber, whole foods; reduce ultra-processed and added sugars.
   • Training: 2–4 days resistance + daily zone-2/steps; add mobility.
   • Stress: 5–10 minutes daily breathwork; morning light exposure.
4. Consider add-ons last. Peptides, advanced biologics, and wearables can augment—they don’t replace the basics.

Resources mentioned (non-sponsored)

• Epigenetic clocks: Horvath, GrimAge, DunedinPACE (for pace-of-aging feedback in ~8–12 weeks).
• Comprehensive lab panels: Options like Function Health or through your functional medicine provider.
• Reading list: The Culture Code (Daniel Coyle)—Greg’s pick on why culture matters in any team, including your health team.

About our guest

Greg Shindler is an entrepreneur and longevity evangelist who helps high performers approach health with a CEO mindset. He previously operated clinics focused on biologics and longevity.

Disclaimer

This conversation is for educational purposes only and is not medical advice. Always consult a qualified healthcare professional before starting or changing any health regimen.

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