From the University of California San Francisco, Dr. Michael Blum, CMIO, and Dr. Russell Cucina, Associate Medical Director of IT, discuss UCSF’s employment of clinical documentation in advance of computerized practitioner order entry (CPOE). Dr. Blum and Cucina describe the initial requirements, success criteria, challenges and lessons learned of establishing clinical documentation prior to CPOE. The interview is conducted by Dr. William F. Bria, Chief Medical Information Officer, Shriners Hospital for Children, and Chair of the HIMSS/AMDIS Physician Community.