In this episode, Dr. Jesse Boehm discusses the importance of collaboration in cancer research. Dr. Boehm touches on some of the partnerships that he has been involved in, such as the large collections of organoids and cell models in the Human Cancer Models Initiative. Although logistical and bureaucratic can challenge these cross-institutional partnerships, Dr. Boehm shares the key ingredients that make collaboration more feasible. Dr Boehm also notes that the urgency seen during the recent pandemic should be applied to cancer research to drive significant progress.