ENT Update 頭頸外科與腫瘤學專題 2026/05/11 (台北時間週一)

本集討論三篇頭頸外科與腫瘤學最新文獻：

【論文一：螢光導引冰凍切片在頭頸癌邊緣控制】

► Intraoperative fluorescence-guided fresh frozen sectioning for margin control in head and neck cancer: phase 2 clinical trial

Nature Communications, 2026 Mar 10

DOI: 10.1038/s41467-026-70264-y

PMID: 41807438

【論文二：新輔助免疫化療後頭頸癌手術最佳時機】

► Optimal timing of surgery in head and neck squamous cell carcinoma after neoadjuvant immunochemotherapy

Frontiers in Oncology, 2026 Feb 6

DOI: 10.3389/fonc.2026.1742883

PMID: 41727640

【反向文獻討論】

► Unraveling resistance to immune checkpoint inhibitors in HNSCC

Cancer Drug Resist, 2025

https://www.oaepublish.com/articles/cdr.2025.153

► Inflammation and limited adaptive immunity predict worse outcomes on immunotherapy in head and neck cancer

npj Precision Oncology, 2025

DOI: 10.1038/s41698-025-01020-6

【論文三：AI多體學免疫亞型分類預測HNSCC免疫治療反應】

► Integrative immune subtyping of HNSCC reveals clinically relevant phenotypes for immunotherapy response prediction

npj Precision Oncology, 2026 Apr 23

DOI: 10.1038/s41698-026-01440-y

主持人：傅醫師（引導）、林醫師（批判辯證）