In this conversation, Dr. Devon Christie shares her journey from traditional medicine to the innovative field of psychedelic-assisted therapy. She discusses the founding of the Center for Medicine-Assisted Therapy (CMAT), describing the challenges posed by regulatory frameworks in Canada, particularly regarding the approval of MDMA and psilocybin therapies. Devon highlights the need for education and harm reduction in the context of psychedelic use, advocating for a balanced approach that prioritizes patient safety and well-being. Together, Devon, Andrew and Joe explore the complexities of psychedelic therapy, emphasizing the need for advocacy, regulation, and training for therapists. They discuss the importance of self-awareness, community support, and the integration of indigenous wisdom into therapeutic practices. The conversation highlights the challenges of navigating the ethical landscape of psychedelic work. Devon offers the 'Five Invitations' framework as a guiding principle for practitioners. The speakers also stress the significance of rituals in therapy and the necessity of cultural sensitivity when working with diverse populations.