In this episode, our host, Dr. Paulo Sales, interviews Dr. Mike Saag to condense high-yield information on infectious diseases that the consultation-liaison psychiatrist should be aware of. Among other topics, Dr. Saag discusses the recent advances in Mpox and the role of vaccination and prevention, monitoring and treatment of common sexually transmitted diseases that may affect people living with HIV while summarizing clinical pearls in treating comorbid Hepatitis B and C, among other topics.